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Splice
Overlook Pick

Splice

She's not human...not entirely.
59
User Score2,461 ratings
TMDB 5.916+20101h 44mEnglish
HorrorScience Fiction

Synopsis

Elsa and Clive, two young rebellious scientists, defy legal and ethical boundaries and forge ahead with a dangerous experiment: splicing together human and animal DNA to create a new organism. Named "Dren", the creature rapidly develops from a deformed female infant into a beautiful but dangerous winged human-chimera, who forges a bond with both of her creators - only to have that bond turn deadly.

Director
Vincenzo NataliFrom TMDB credits
Studio
Copperheart Entertainment4 production companies
Release
June 3, 2010Released
Box Office
Budget $26M

Top Cast

8 of 9
Adrien Brody
Adrien Brody
Clive
Sarah Polley
Sarah Polley
Elsa
Delphine Chanéac
Delphine Chanéac
Dren
David Hewlett
David Hewlett
Barlow
Abigail Chu
Abigail Chu
Young Dren
Stephanie Baird
Stephanie Baird
Elsa / PD
Brandon McGibbon
Brandon McGibbon
Gavin
Amanda Brugel
Amanda Brugel
Melinda Finch

Trailers & Photos

Reviews

From TMDB users
Andres Gomez
Nov 26, 2014

The FX is OK and the uneasiness and thrill is always there but the script is stereotypical, weak and full of holes.

John Chard
Dec 2, 2018

Brundledren! Splice is a tricky picture to evaluate, for its ideas are superb. One could argue that it brings a new petri dish full of meddling scientists facing the consequences of their actions, while conversely it justifiably feels like a Cronenberg knock-off. Psychological discord is in abundance, with its slants on skew-whiff parenting giving the pic a dark fascination, and as unpleasant as the male fantasy angle is, it does hold a morbid interest factor. Yet come the final third the makers let things run away from them, the bonkers dangers of tampering with science giving way to daft schlock, even managing to be distasteful in the process - while the finale is a weak attempt at a "TBC" cliff hanger. Lead cast members are turning in good perfs. Adrien Brody and Sarah Polley as the meddling science couple hold court well, and Delphine Chaneac as the Chimera splicer of the piece really nails all the various emotional strands required for a tricky role. Director Vincenzo Natali has shown with Cube and Cypher he has something to offer the horror/sci-fi splinters of film, but this is a mixed bag. A film of great ideas let down by overheating the plot for shock values, while the levity inserted into the play is misguided and damaging for dramatic worth. 6/10

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