In August 2000, 17-year-old Jessica Carpenter is found murdered in her Aiken, S.C., home by her mother; local reporters and family members tell the story of a town frozen in terror as police search for a possible serial killer on the loose.

When 15-year-old high school freshman Danielle Locklear, of Hope Mills, N.C., went missing in March 2014, her family and friends think a killer is in their midst, then a body is found in a creek near South River, weighed down with concrete blocks.

When 44-year-old high school teacher, Theresa Lockhart, of Portage, Mich., went missing in May 2017, her vehicle is discovered with nothing inside and as police begin the investigation as a possible homicide, with her husband as a person of interest.

Forty-year-old Rachael Anderson disappears without a trace after calling a friend about a home improvement project she'll never complete.

After 19-year-old college co-ed, Jessica O'Grady, went missing one night in May 2006, after leaving to see her boyfriend in Omaha, Neb., another woman disappears a week earlier which causes the locals to wonder if a serial killer is on the loose.

When the body of 19-year-old Ali Kemp was found by her father at a swimming pool in Leawood, Kan., in June 2002, her father goes on a quest to find is daughter's killer; news reports and interviews with investigators and family are featured.